Jurnal Media Penelitian dan Pengembangan Kesehatan

KOMBINASI KACANG MERAH DAN KULIT KACANG HITAM PADA TIKUS WISTAR MODEL DIABETES MELITUS TIPE 2

Pratiwi Wulandari, Adi Magna Patriadi Nuhriawangsa, Tri Nugraha Susilawati — Mon, 19 Feb 2024 00:00:00 +0800

Type 2 Diabetes Mellitus (T2DM) is a metabolic disease that require pharmacological and non-pharmacological therapies. Comsuming functional foods that are high in antioxidants and fiber such as red beans and black beans beneficial to patients with T2DM. The study aimed to examine the effect of the combination of red beans (Phaseolus vulgaris L.) flour and black beans (Phaseolus vulgaris) coat extract on body weight, blood glucose, insulin level and pancreatic tissue of T2DM model rats. This randomized controlled trial involved 36 male Wistar rats divided into 6 groups consisted of non-diabetic rats (Group I) and nicotinamide-streptozotocin induced diabetic rats (Group II-VI). Group II was negative control; Group III-V were given a combination with the proportion of flavonoid/ fiber in each kgBW as follows: 22.5 mg/0.25 g; 45 mg/0.5 g; and 90 mg/1 g. Group VI was the positive control. Data on body weight, fasting blood glucose levels and insulin levels were analyzed using Two-Way Anova, while pancreatic histopathology scoring data used Kruskal-Wallis.There was a significant difference between the dose and duration of intervention on body weight, fasting blood glucose and insulin levels (p=0.001). The intervention groups showed there were no pancreatic histopathology change as good as the positive control (p>0.05). The combination of flavonoids and fiber at a dose of 45 mg/0.5 g per kgBW was proven to gain weight, reduce fasting blood glucose levels, increase insulin levels and no pancreatic histopathology change in T2DM rats models as well as the postive control group.

ANALISIS PEMBUATAN DAN POTENSI EKOENZIM KULIT BUAH JERUK NIPIS (Citrus aurantiifolia) SEBAGAI UPAYA PENINGKATAN KESEHATAN MANDIRI RUMAH TANGGA

Hupitoyo Hupitoyo, Tanto Hariyanto, Atik Kurniawati — Tue, 20 Feb 2024 00:00:00 +0800

Lime peel ecoenzyme (Citrus aurantifolia) is a microbial-based product made by fermenting the fruit peel for more than one month. The study aimed to analyze the ecoenzyme product from lime peel (C. aurantifolia) and its potential as an antiseptic so that it becomes one of the independent health improvement efforts on a household scale. The research design was laboratory experiments. The data described descriptively based on the results obtained from laboratory experiments. The research results showed that ecoenzyme contains a complex of organic ingredients as a natural antiseptic that can be used in the household such as 19 types of organic acids, 17 types of flavonoids, 16 types of carbohydrates and 19 types of amino acids which have potential as antiseptics. The study concluded that the ecoenzyme product from lime peel (C. aurantifolia) has potential as an antiseptic because it contains a complex of organic ingredients as a natural antiseptic that can be used in the household. Potential antiseptics can be in the form of dish cleaners, fruit and vegetable washes. Instead of being an antiseptic, ecoenzyme liquid can be used as a plant fertilizer and compost activator which can be applied to reduce household waste.

SENAM ASIK DAPAT MENURUNKAN NYERI MUSKULOSKELETAL PADA KELOMPOK WANITA TANI

Tue, 20 Feb 2024 00:00:00 +0800

Work-related musculoskeletal pain is a serious occupational health problem worldwide. Farmers are one of the groups of people who are most at risk of developing this condition. To help reduce musculoskeletal pain, farmers can participate in a exercise program called "Anti Sakit Ibu Kelompok wanita tani" (ASIK). The purpose of this study is to analyze the effect of ASIK-exercise on musculoskeletal pain in a group of women farmers in Karanganyar. The study used a pre-test and post-test design. The sampling technique used was purposive sampling, with a sample (respondents) of 19 women farmers who met the inclusion and exclusion criteria. The inclusion criteria were active members of the women farmers' group, in good health, and living in the village of Bolon. The exclusion criteria were respondents who could not read or write, and who were unable to do exercises due to physical constraints. The independent variable was ASIK gymnastics, the dependent variable was musculoskeletal pain, and the control variable was age. The analysis of the difference in musculoskeletal pain scores before and after ASIK-exercises without controlling age used a paired samples t-test, and the analysis of the difference in musculoskeletal pain scores before and after ASIK-exercises with age as a covariate was performed using ANCOVA at α = 5%. The test results stated that with controlling age, ASIK-exercises can significantly reduce musculoskeletal pain (F = 7.540; p = 0.009) with a large effect size category (d = 1.68).

ANALISIS DENGAN METODE ETHNONURSING LEININGER PREVALENSI KUSTA: SOSIAL, BUDAYA DAN PERAN TENAGA KESEHATAN

Tue, 20 Feb 2024 00:00:00 +0800

Leprosy has not been eliminated in six provinces in Indonesia, one of which is Papua. Mappi Regency, Papua, contributed one thousand cases of leprosy in the last five years and 100 active cases in 2020. The high leprosy prevalence in Mappi Regency is still a mystery of the main cause. It is necessary to explore the causes of the high prevalence of leprosy in the region. The study aimed to explore socio-cultural factors and the role of health workers on the prevalence of leprosy in Mappi Regency, Papua, Indonesia. The study method was Qualitative ethnonursing by purposive sampling. This research was conducted in Mappi Regency. Data saturation was obtained from fourteen informants: four leprosy patients, four leprosy patients' families, three health workers, and three stakeholders in Primary Health Center Kepi, Kota 2, Senggo, and Health Office Mappi. Data retrieval and processing with Leininger's Ethnonursing analysis was assisted by Atlas.ti application. The study result showed there were seven emerging themes, including social and cultural: leprosy is considered like a common disease, changes in economic situation, affordability and geographical conditions, leprosy care by patients, families, and communities, suboptimal practices of health workers, limited role of government, budget, and logistics, and expectations for handling leprosy cases. The study concluded that social and cultural factors and the role of health workers contribute to the prevalence of leprosy in Mappi District, Papua, Indonesia. Strengthening the role of families, communities, health workers, and government policies is needed to support the recovery of leprosy patients and reduce the prevalence of leprosy.

DIABETES SELF MANAGEMENT TERHADAP HBA1C DAN KADAR GULA DARAH PADA KELOMPOK PREDIABETES SEBELUM DAN SESUDAH INTERVENSI

Kartini Muhamad Ali, Rusny Muhammad — Wed, 21 Feb 2024 00:00:00 +0800

Prediabetes is a condition in which a person has blood glucose levels that are higher than normal but not yet high enough to be classified as diabetes. The aim of this study was to determine the effect of diabetes self-management on blood sugar and HbA1c levels in the prediabetes group before and after intervention in the Kalumpang Community Health Center working area, Ternate. This research uses the Pre-Experimental method (one-group pre-post test design with control). Based on the data, the number of samples in this study was 25 which included control and intervention groups with a total of 50 samples. Inclusion criteria are individuals who are willing to be respondents, cooperative individuals, individuals aged 45 – 54 years, individuals who are willing to fill out a 24 hour food recall questionnaire, individuals who have HbA1c levels: ≥5.7% - <6.5%, GDP : ≥100- <126 mg/dl and GD2PP :≥140- <200 mg/dl. Meanwhile, the exclusion criteria are individuals who are not willing to be respondents and individuals who are not cooperative. Data analysis to test the results of treatment before and after treatment used the Paired T-Test. The study's results showed a significant difference between the patient's blood sugar and HbA1c before and after the intervention. Compared with the control, there was a significant difference in blood sugar levels and HbA1c between the intervention and control groups. The main finding of this study is that diabetes self-management has an impact on HbA1c and blood sugar levels in the prediabetes group.

ANTIOXIDANT, DIETARY FIBER, AND ORGANOLEPTIC IN CHOCO DRINK FORMULA WITH ADDED SORGHUM FLOUR

Rosalinda Abir Hanifah, Budiyanti Wiboworini, Veronika Ika Budiastuti — Mon, 26 Feb 2024 00:00:00 +0800

Pangan fungsional bermanfaat mencegah atau mengurangi risiko penyakit. Coklat dan sorgum mengandung polifenol sebagai antioksidan. Tujuan penelitian ini untuk menganalisis tingkat kesukaan dan kandungan gizi produk choco drink sebagai minuman alternatif yang mengandung antioksidan dan serat pangan. Produk choco drink terdiri atas 4 kelompok: choco drink tanpa tepung sorgum (C), choco drink dengan tepung sorgum 10 gr (S10), 20 gr (S20), dan 30 gr (S30). Penelitian ini terdiri dari pengujian kandungan zat gizi dan uji hedonik oleh 29 panelis tidak terlatih yang dipilih secara accidental sampling. Kandungan gizi produk dianalisis menggunakan uji One way ANOVA dan uji hedonik produk dianalisis menggunakan uji Kruskal wallis. Analisis uji kandungan gizi produk menunjukkan terdapat perbedaan kandungan energi, karbohidrat, protein, lemak, serat pangan, air, dan antioksidan pada keempat produk choco drink (ρ<0.05). Analisis uji hedonik keempat produk menunjukkan terdapat perbedaan tingkat kesukaan panelis dari segi rasa (ρ=0.002) dan tekstur (ρ=0.000), sedangkan hasil analisis segi warna dan aroma menunjukkan tidak terdapat perbedaan (ρ>0.05). Penelitian ini dapat disimpulkan bahwa sebagian besar panelis menyukai produk C yaitu tanpa penambahan tepung sorgum dengan kandungan serat pangan 0.28 gr dan aktivitas antioksidan 44.95%.

KAJIAN KEBIJAKAN IMPLEMENTASI PROGRAM KESEHATAN REPRODUKSI REMAJA UNTUK MENGHASILKAN MODEL PEMBERDAYAAN REMAJA

Rugaya Munawar Pandawa, Nuzliati T Djama — Fri, 01 Mar 2024 00:00:00 +0800

It is hoped that the existence of a youth posyandu will become a forum for empowering teenagers, especially those who have limited access or geographical barriers such as remote areas, island areas, outermost or isolated areas. The aim of this research was to examine the policy of the Adolescent Reproductive Health (KRR) program implemented by the community health center and develop a policy model for adolescent empowerment. This policy study research is a qualitative study using interviews and FGDs to examine the implementation of the KRR program and the results can develop strategic policies. The researcher then conducted a Focus Group Discussion. Total of 16 posyandu from 8 community health centers in Morotai Island Regency were chosen as research locations. Data collection during August 2023. Only 4 community health centers have active posyandu (Daruba, Sangowo, Morodadi, and Tiley), 1 community health center (Wayabula) has joined Posbindu, 3 youth posyandu are integrated with the School Health Unit (UKS) program implemented in junior and senior high schools. Data analysis was carried out using theme analysis. Facilities and infrastructure have not been met according to standards and guidelines are incomplete at the youth posyandu. Most teenagers are less active in using youth Posyandu if it is implemented in villages compared to implementation in integrated schools with the UKS program. In conclusion, the achievement of the KRR program objectives has not been optimal. The development of a youth empowerment policy model is carried out based on the resulting policy brief.

HUBUNGAN ANTARA AKTIVITAS FISIK DAN POLA TIDUR DENGAN KEJADIAN HIPERTENSI

Wed, 13 Mar 2024 00:00:00 +0800

Hypertension is a non-communicable disease which is currently the main cause of health problems. The research aimed to determine the relationship between physical activity and sleep patterns and incidence of hypertension in the Pancasan Community Health Center Area, Bogor City. This research was quantitative research with observational methods using a cross-sectional design. This research used the Chi square analysis test. This research was conducted in the working area of the Pancasan Health Center in Bogor City for 4 months from April to July 2023. Sample inclusion criteria are domiciled in the Pancasan Community Health Center working area, hypertensive and non-hypertensive patients aged 21-60 years, hypertensive patients with systolic blood pressure of 140-179 mmHg and diastolic blood pressure of 90-109 mmHg, and who are willing to be respondents by signing the information consent when collecting data for both patients with hypertension and without hypertension. Sampling in this study was done using the simple random sampling technique. The sample size in this study used the Lemeshow Formula so 57 samples were obtained. The results showed an association between the level of physical activity and the incidence of hypertension (P=0.028) and a relationship between hypertension and poor sleep patterns (P=0.003). In conclusion, low physical activity increases the risk of hypertension, while moderate activity has four times the chance of not developing hypertension. Sleep patterns are significantly related to the incidence of hypertension where respondents who have good sleep patterns have a lower chance of developing hypertension compared to respondents who have poor sleep patterns.

DETERMINAN IMUNISASI DASAR PADA BALITA DI INDONESIA: STUDI PEDESAAN

Rizky Indah Syahfitri, Zata Ismah, Nofi Susanti — Wed, 13 Mar 2024 00:00:00 +0800

According to the results of the Riskesdas report, basic immunization coverage in Indonesia in 2017 only reached 59.4% and 57.9% in 2018. This figure is still far from the strategic plan target set by the Ministry of Health in 2019, namely 93%. The research aimed to analyze the factors that influence the incomplete basic immunization status of children in rural areas, Indonesia. This research is a quantitative research designCross Sectional. The data used is secondary data originating from the 2017 Indonesian Demographic and Health Survey (SDKI). The sampling technique usedtotal sampling amounting to 3,111 children under five. Based on the results of this study, it can be concluded that the determinants of incomplete basic immunization for toddlers in rural areas of Indonesia are less than 3 antenatal visits, delivery not in a health facility, distance to health facilities is a big problem, mother's age is less than 25 years, father's education is low, and the order of the 3rd child, etc. The chance of children not having complete basic immunization for toddlers in rural areas of Indonesia if all risk factors are present is 86%. The most dominant risk factor influencing incomplete basic immunization status is fewer than 3 antenatal visits. It is recommended that health workers prioritize health promotion programs regarding the benefits of antenatal visits by approaching community leaders, especially midwives.

HUBUNGAN PARITAS DAN ANEMIA DENGAN PERSALINAN PREMATUR

Syamsul Bahri Riva'i, Ratih Ayuningtyas, Thalia Shalsabillah — Wed, 20 Mar 2024 00:00:00 +0800

Premature birth is the main cause of high perinatal mortality rates. The lower the birth weight, the higher the incidence of morbidity and mortality. WHO says there are 15 million babies born prematurely every year throughout the world. Of the 15 million premature babies, 1.1 million babies were reported to have died due to various complications. Premature birth and complications in labor are always associated, such as asphyxia, infection and birth defects, which are the cause of most neonatal deaths. The aim of this study was to determine the relationship between parity and anemia with the incidence of preterm labor. This research is a quantitative observational analytical study with an individual matched case-control design, a retrospective approach using secondary data from mothers giving birth in the Obstetrics and Obstetrics Department of Arifin Achmad Hospital Riau for the period January 2016 – December 2018 which was carried out in May – June 2023. The sample size was 259 cases and 259 controls. From the parity chi-square test carried out, a p-value of 0.855 (≥ 0.05) was obtained, where it was concluded that there was no relationship between parity and the incidence of premature labor and from the chi-square test for anemia, a p-value of 0.00 was obtained ( <0.05) so it can be concluded that there is a relationship between anemia in pregnancy and OT at Arifin Achmad Hospital, Riau Province. It is recommended that pregnant women check their HB levels to avoid amenia which can cause premature labor and also to avoid other factors that cause premature labor.

ASPERGILLOMA PADA TUBERKULOSIS PARU: LITERATURE REVIEW

Wily Arianto, Rohani Lasmaria — Fri, 22 Mar 2024 00:00:00 +0800

Indonesia ranking among the top six countries with the highest TB burden. In the aftermath of pulmonary TB, fungal infections, particularly those caused by Aspergillus species, have emerged as a notable complication. The predominant species, Aspergillus fumigatus, is responsible for a spectrum of conditions ranging from invasive to noninvasive aspergillosis. This literature review aims to provide an exhaustive analysis of post-TB pulmonary aspergilloma, a clinical condition characterized by the growth of Aspergillus fungal balls within pre-existing lung cavities. Utilizing databases such as PubMed, Science Direct, EBSCO, Emerald, Scopus, and Google Scholar, and employing keywords such as "tuberculosis," "aspergillus," "aspergilloma," and "pulmonary," we meticulously applied the PICO framework and the CRAAP (Currency, Relevance, Authority, Accuracy, and Purpose) criteria to select 20 pertinent articles. The findings indicate that pulmonary aspergilloma manifests in approximately 11% to 17% of individuals post-TB treatment, presenting a clinical spectrum from asymptomatic to severe, life-threatening hemoptysis. Classification into simple and complex aspergilloma is based on specific clinical and radiological criteria. Diagnosis is contingent upon the identification of clinical symptoms, assessment of risk factors, and the corroboration of Aspergillus infection through radiological (chest X-ray and CT scan) and serological or microbiological evidence. Management of pulmonary aspergilloma entails non-operative and operative strategies, with surgical intervention being the definitive treatment, especially in cases of recurrent or massive hemoptysis. The review underscores the persistent challenge of TB in Indonesia, exacerbated by secondary fungal infections such as aspergillosis among pulmonary TB survivors. Aspergillus fumigatus is identified as the primary fungal pathogen, leading to pulmonary aspergilloma.

IMPELEMENTASI POTENTIAL HAZARDS PELAYANAN RUMAH SAKIT DENGAN MENGGUNAKAN METODE JOB SAFETY ANALYSIS

Mon, 25 Mar 2024 00:00:00 +0800

Potential dangers in hospitals, apart from infectious diseases, there are also other potential dangers, namely accidents, radiation, anesthetic gasses, psychosocial and ergonomic disorders. The study aimed to analyze the implementation of potential dangers of hospital services using the method Job Safety Analysis at the Regional Hospital X. This type of research is descriptive. a sample of 7 people who work in the Emergency Unit, through an approach accidental sampling. The research variable is the potential for danger in the UGD Regional Hospital X. The instrument used is the JSA instrument. The data obtained is presented in the form of a narrative and a matrix of in-depth interview results. Respondents who carry out potentially dangerous work according to the JSA method are doctors and nurses who provide services in the Emergency Unit. The work carried out is lifting and moving patients, giving injections, using ventilators, using EKGs, using monitor units, using section units and workload. Respondents who carry out potentially dangerous work according to the JSA method are doctors and nurses. Potentially dangerous facilities are syringes, ventilators, sections, masks, stethoscopes, cuffs, EKGs, ventilators, section units. For the Regional Hospital X to provide outreach about occupational safety and health management in the hospital to all employees so that they know the risk of work accidents and make an analysis of potential hazard methods according to the JSA method so that doctors and nurses know the level of risk of work accidents when providing services.

ORAL NUTRITION SUPPLEMENT (ONS) BERBASIS BAHAN PANGAN LOKAL UNTUK PASIEN MALNUTRISI RUMAH SAKIT

Mona Fitria, Maryati Dewi, Dieni Wulandari — Sun, 31 Mar 2024 00:00:00 +0800

Hospitalized patients with malnutrition are at risk of experiencing prolonged healing processes, extended hospital stays, and a decline in quality of life. One effort to enhance energy and protein intake is through oral administration using Oral Nutrition Supplements (ONS). ONS can be developed as a liquid food formula based on local ingredients, such as tilapia fish and sweet potato. This research aimed to determine the impact of tilapia fish flour and sweet potato flour formulations on the quality of ONS, including organoleptic properties, nutritional value, physical quality, microbiology, and shelf life. The experimental design involves three formulations of tilapia fish and sweet potato flour: 80%:20% (F1), 60%:40% (F2), and 40%:60% (F3). Organoleptic properties are analyzed using hedonic tests by 30 semi-trained panelists. The results showed that ONS with the best organoleptic properties was F2, with an average hedonic score of 5.60 (overall). Kruskal-Wallis test results showed that the formulation significantly influences the taste, aroma, color, and overall of ONS. Nutritional analysis revealed that ONS F2 per 100 mL contains 112 Kcal of energy, 5.4 g of protein, 3.8 g of fat, and 14.1 g of carbohydrates. The viscosity of ONS F2 was 226.5 cP, and the osmolality was 589 mOsmol/kg H₂O. ONS F2 also complied with microbiological quality standards. The shelf life of ONS F2 at 2°C was estimated to be 24 days, with an expected selling price of Rp. 23,000 per serving. The research results are expected to apply to malnourished patients in hospitals.

ANALISIS FAKTOR RISIKO DISMENORE PRIMER DAN DISMENORE SEKUNDER PADA MAHASISWI

Sun, 31 Mar 2024 00:00:00 +0800

While the incidence of dysmenorrhea is relatively high worldwide, the prevalence of dysmenorrhea reported in the literature varies substantially. This study aimed to analyze the risk factors for primary dysmenorrhea and secondary dysmenorrhea. This research is a cross analytical design. The sample in this study was all medical faculty students at Riau University in 2019-2022, namely 410 people. From the research results, it was found that there was a relationship between menstrual blood volume, history of food allergies and stress with the incidence of primary dysmenorrhea. Meanwhile, the incidence of secondary dysmenorrhea was related to age, menstrual cycle, history of the sample's gestational age at birth, history of low birth weight (LBW), history of emotional violence, stress and birth history of samples from preeclamptic mothers at the time of delivery. This research concluded that there were several significant findings regarding factors related to the occurrence of dysmenorrhea in Riau University medical students in 2019 - 2022. The research showed the importance of paying attention to factors such as the length of the menstrual cycle, history of food allergies, history of emotional violence, stress, and history of maternal preeclampsia in efforts to prevent and manage dysmenorrhea in the population. It is recommended that future research further explore the association between the identified risk factors and the incidence of dysmenorrhea, potentially revealing additional insights to guide clinical practice and public health initiatives.

PENGEMBANGAN MEDIA VIDEO EDUKASI GIZI SEIMBANG SEBAGAI UPAYA DALAM PENCEGAHAN PENYAKIT TIDAK MENULAR PADA REMAJA

Umi Mahmudah, Witri Priawantiputri — Sun, 31 Mar 2024 00:00:00 +0800

Teenagers are a group vulnerable to obesity. Obesity is one of the main causes of non-communicable diseases (NCDs). Diet is the most influential risk factor for obesity. Nutrition education is one way to prevent obesity. Educational media is the key to the success of nutrition education. Video is an audio-visual media that displays material that can provide students with real experiences. The research aimed to develop balanced nutrition video nutrition education media for teenagers and determine the suitability of nutrition education video media to be applied as educational media. This research was development research using steps (1)analysis: analyzing problems, needs, goals (2)design: making scripts and storyboards. (3)development: producing videos. (4)implementation: testing feasibility by media and material experts and teenagers in SMAN 1 Cimahi has 30 students as a potential user, review, revision. (5)evaluation: evaluate the results, and carry out revisions. The research results obtained 2 series of animated videos, namely series 1 regarding prevention of non-communicable diseases and series 2 regarding balanced nutrition. The average validation results on animated video 1 by media experts were 95.26%, material were experts 87.85%, while the average validation results on animated video two by media experts were 92.26%, material experts 92.14%. The validation results by material experts and media experts on animated video series 1 and 2 were declared very valid. The results of student trials as users showed that animated video media 1 and 2 can be well received by potential users. The animated video media series 1 and 2 can be used as media for nutrition education, especially for teenagers.

EFEKTIVITAS EDUKASI ANTENATAL TERHADAP KETAKUTAN DAN EFIKASI DIRI PERSALINAN PADA PRIMIPARA: SYSTEMATIC REVIEW

Syamsuriati Syamsuriati, Imami Nur Rachmawati, Wiwit Kurniawati — Sun, 31 Mar 2024 00:00:00 +0800

Fear of giving birth due to lack of knowledge causes a decrease in primigravida mothers' confidence in their ability to undergo childbirth. Decreased self-efficacy in childbirth can cause birth complications such as prolonged labor, fatigue and weakness in the mother, which results in the mother's failure to undergo a natural birth. Antenatal education is an appropriate alternative to increase mothers' knowledge of the birth process. The aim of the research was to examine the effectiveness of antenatal education in reducing fear of childbirth and increasing childbirth self-efficacy in primiparous mothers. The structure of this research is a detailed analysis using the PRISMA flow diagram. Researchers applied the PICO method and searched for articles in English published between 2018 and 2023. Some of the databases used included Proquest, PUBMED, Sage Journal, Springer Link, Science Direct, EBSCO, Plos One and Taylor & Francis. Article quality assessment using JBI Critical Appraisal Tools for RCT. Seven articles were identified and analyzed, all articles used a Randomized Controlled Trial design. The research sample numbered 56 to 182, consisting of primiparas in the age range 18-32 years with a gestational age of <34 weeks and was conducted in Saudi Arabia, Turkey, Iran and China. From the literature search, in general it can be concluded that antenatal education provided to primiparous mothers is effective in reducing fear of childbirth and increasing self-efficacy in childbirth.

DAYA HAMBAT DARI EKSTRAK SARANG BURUNG WALET PADA PERTUMBUHAN BAKTERI STREPTOCOCCUS MUTANS DAN PORPHYROMONAS GINGIVALIS

Ulfah Utami, Megananda Hiranya Putri, Neneng Nurjanah, Eldarita Eldarita — Sun, 31 Mar 2024 00:00:00 +0800

Type 2 diabetes (T2DM) is one of the fastest growing global diseases of the 21st century, with its prevalence more than tripling in the last 20 years and affecting 10.5% of the world's population aged 20-79 years. In Indonesia, diabetes mellitus among 20-79 year olds is 10.6%. The most widely cultivated type of swallow nest is Collocatia fuciphaga. Collocatia fuciphaga is a species of bird that produces nests from its white saliva. Swallow's nest contains sialic acid which is only produced from saliva, calcium, glycoproteins and Epidermal Growth Factor (EGF), one of the benefits of which is to accelerate wound healing. The study aimed to determine the inhibition of swallow's nest extract on the growth of Streptococcus mutans and Porphyromonas gingivalis bacteria. The swallow's nest extract test used an experimental design approach, namely conducting laboratory tests. The initial stage was to make swallow's nest extract by maceration technique using 96% ethanol solvent (the aim is to get anti-bacterial active substances, namely D-Galactose and Sialic acid contained in swallow's nest), the result of the extraction was a dry extract weighing 1.8195 grams which was then dissolved again using DMSO solution with concentrations of 10%, 20%, and 30%. The second stage is the swallow's nest extract test with the two test bacteria. The results of the swallow's nest extract test at concentrations of 10%, 20%, 30% against Streptococcus mutans and Porphyromonas gingivalis bacteria showed no inhibition. Future research could be further developed toward wound healing